Sperm sex selection and motility sorting services

1. Development Concept: This service is designed for animals that require selective breeding and increased reproductive success.

2. Launch Date: 2024

3. Manufacturer: Cell 3S bank, designing and manufacturing.

4. Product Specifications: This service utilizes "physical" sorting through sorting chips, thus causing no damage to the sperm itself. Up to 80% of specified sexed sperms can be selected.

5. Uniqueness: While there are sperm vitality sorting and sexed sorting techniques exist on the market, however, no other technology integrates both functions.

6. Related Certifications: Patents are held in Taiwan, the United States, and China. Such as TWI503415, TWI773159, US9,023,613, US20220283071A1, CN114989935A.

7. Applicable Objects: Applicable to all species that achieve fertilization through cervical artificial insemination(CAI), with the ability to both enhance vitality and specified gender.

8. Usage Benefits: Can select sperm with high vitality and accurately specified gender, greatly improving fertilization and reproductive rates.
National Tsing Hua University's (Startup : Cell 3S bank) sex sorting chip can effectively distinguish between X and Y sperm. Unlike flow cytometry, our chip does not harm sperm and can be used in conjunction with our sperm vitality sorting chip to provide "sex-selected" and "highly motile" sperms. This semen can be used for animals with high sperm demand. Therefore, in addition to pigs, it can also be extended to other animals requiring gender selection in the future. At present, our company is cooperating with the Academy of Agricultural Sciences to verify the integrity of this technology. After two IVF trials, the XX ratio in the fertilized eggs (pig) has 4-fold enhancement as compared to the control group.

Currently, the main sex sorting technology in the world still uses flow cytometry separation technology. However, the instruments are very expensive, and the number of sperm is small. It is only suitable for dairy cows (cattle) and is not sufficient for field insemination of pigs. In view of this, our company's sex sorting chip technology not only shortens the operation time, but also does not cause any damage to sperm. The number of sperm sorted at a time is three orders of magnitude more than that of flow cytometry separation technology. In addition, the sex sorting chip has been tested and found to be durable for up to five times of repeated use, which greatly reduces the cost. The most important thing is that the applicable species are no longer limited to ruminants, but all economically important species with sex selection needs on the market.